Structure Viewer: 6lfx

>   Structure details

Crystal Structure of Pcb4Scfv(Hn56D) in complex with Pcb#77

PDB6lfx
SpeciesMUS MUSCULUS
MethodX-RAY DIFFRACTION
Resolution1.43Å
Number of Fvs1
In complexTrue
Light chain typeunknown
Has constant regionFalse
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>   Fv information

This PDB has 1 Fv(s).

>   A/A
Fv Details
Heavy chainA
Light chainA
Heavy subgroupunknown
Light subgroupunknown
SpeciesMUS MUSCULUS
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 101 102 103 104 105 106 107 108 109 110 111 112 113
E V K L V E S G G G L V K P G G S L K L S C A A S G F T F S T Y G M S W V R Q T P E K R L E W V A S I S G G G D T Y Y T D I V K G R V T I S R D N D R N I L Y L Q M S S L R S E D T A M Y H C T R G A L V R L P H Y Y S M D Y W G Q G T S V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q T A S S L S A S L G D R V T I S C R A S Q Y I N N Y L N W Y Q Q K P D G T V T L L I Y Y T S I L H S G V P S R F I G S G S G T D Y S L T I S N L D Q E D I A T Y F C Q Q G Y T L P L T F G A G T K L E L K

Antigen Details
Antigen chainsa
Antigen typeHapten
Antigen name1,2-bis(chloranyl)-4-(3-chloranyl-4-methoxy-phenyl)benzene
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequence

CDR Sequences (chothia definition)
CDRH1GFTFSTY
CDRH2SGGGD
CDRH3GALVRLPHYYSMDY
CDRL1RASQYINNYLN
CDRL2YTSILHS
CDRL3QQGYTLPLT

Orientation Angles (from ABangle)
HL-65.77°
HC171.23°
HC2117.69°
LC1118.24°
LC281.42°
dc15.82Å
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Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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