Structure Viewer: 6o89

> Structure details

anti-Cd28Xcd3 Codv Fab

PDB	6o89
Species	HOMO SAPIENS
Method	X-RAY DIFFRACTION
Resolution	2.09Å
Number of Fvs	2
In complex	False
Light chain type	Kappa,NA
Has constant region	False

> Fv information

This PDB has 2 Fv(s).

Fv Details
Heavy chain	H
Light chain
Heavy subgroup	IGHV3
Light subgroup	NA
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	False

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	52B	52C	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	T	F	T	K	A	W	M	H	W	V	R	Q	A	P	G	K	Q	L	E	W	V	A	Q	I	K	D	K	S	N	S	Y	A	T	Y	Y	A	D	S	V	K	G	R	F	T	I	S	R	D	D	S	K	N	T	L	Y	L	Q	M	N	S	L	R	A	E	D	T	A	V	Y	Y	C	R	G	V	Y	Y	A	L	S	P	F	D	Y	W	G	Q	G	T	L	V	T	V	S	S

CDR Sequences (chothia definition)
CDRH1	GFTFTKA
CDRH2	KDKSNSYA
CDRH3	VYYALSPFDY

Fv Details
Heavy chain
Light chain	L
Heavy subgroup	NA
Light subgroup	IGKV15
Species	HOMO SAPIENS
In complex?	False
scFv?	False
Has constant domain?	False

Numbered Sequences (chothia)

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	Q	A	S	Q	N	I	Y	V	W	L	N	W	Y	Q	Q	K	P	G	K	A	P	K	L	L	I	Y	K	A	S	N	L	H	T	G	V	P	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	I	A	T	Y	Y	C	Q	Q	G	Q	T	Y	P	Y	T	F	G	Q	G	T	K	L	E	I	K

CDR Sequences (chothia definition)
CDRL1	QASQNIYVWLN
CDRL2	KASNLHT
CDRL3	QQGQTYPYT

Additional links and files for download: see help for more details.

Chothia-numbered structure	Download
IMGT-numbered structure	Download
Non-annotated structure from the PDB	Download
Summary file for this antibody	Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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