Structure Viewer: 6pci

> Structure details

Ebov Gpdmuc (Makona) in complex with Rebov-520 and Rebov-548 Fabs

PDB	6pci
Species	HOMO SAPIENS
Method	ELECTRON MICROSCOPY
Resolution	4.12Å
Number of Fvs	6
In complex	True
Light chain type	Kappa
Has constant region	True

> Fv information

This PDB has 6 Fv(s).

Fv Details
Heavy chain	I
Light chain	L
Heavy subgroup	IGHV3
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	100H	100I	100J	100K	100L	100M	100N	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	V	E	E	S	G	G	G	V	V	Q	P	G	G	S	L	R	L	S	C	A	A	S	G	F	M	F	S	N	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	M	A	F	I	R	Y	D	D	S	K	K	F	Y	A	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	S	L	R	A	E	D	T	A	L	Y	Y	C	A	K	E	L	L	Q	V	Y	T	S	A	W	G	E	G	H	S	Y	Y	Y	A	L	D	V	W	G	L	G	T	A	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	V	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	D	I	S	N	W	L	A	W	Y	Q	Q	K	P	G	K	A	P	E	L	L	I	Y	T	A	S	I	L	Q	S	G	V	S	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	S	A	T	Y	Y	C	Q	Q	G	K	S	F	P	Y	T	F	G	Q	G	T	K	L	E	I	K

Antigen Details
Antigen chains	B
Antigen type	protein
Antigen name	virion spike glycoprotein
Antigen species	EBOLA VIRUS
Antigen sequence	SIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSVTKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFT

CDR Sequences (chothia definition)
CDRH1	GFMFSNY
CDRH2	RYDDSK
CDRH3	ELLQVYTSAWGEGHSYYYALDV
CDRL1	RASQDISNWLA
CDRL2	TASILQS
CDRL3	QQGKSFPYT

Orientation Angles (from ABangle)
HL	-61.86°
HC1	68.76°
HC2	120.16°
LC1	121.01°
LC2	80.62°
dc	16.84Å

Fv Details
Heavy chain	P
Light chain	S
Heavy subgroup	IGHV4
Light subgroup	IGKV3
Species	HOMO SAPIENS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	100H	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	Q	E	S	G	P	G	L	G	K	P	S	E	T	L	S	L	S	C	T	V	S	G	A	S	I	R	G	Y	F	W	N	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	Y	I	H	S	T	G	S	T	N	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	V	S	L	N	V	N	S	V	T	A	A	D	T	A	V	Y	F	C	A	R	G	A	W	N	V	A	T	V	Y	Y	Y	Y	G	M	D	V	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
E	I	V	L	T	Q	S	P	G	T	L	S	L	S	P	G	E	R	A	T	L	S	C	R	A	S	Q	S	V	S	S	S	Y	F	A	W	Y	Q	Q	K	P	G	Q	A	P	R	L	L	I	S	G	T	S	T	R	A	P	G	I	P	D	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	R	L	E	P	E	D	F	A	V	Y	F	C	Q	Q	Y	G	N	S	L	Y	T	F	G	Q	G	T	K	L	E	I	K

Antigen Details
Antigen chains	C,F
Antigen type	protein
Antigen name	virion spike glycoprotein; virion spike glycoprotein,virion spike glycoprotein,ebolavirus (makona) gp2
Antigen species	ebola virus ; zaire ebolavirus, ebola virus
Antigen sequence	NNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREVIVNAQPKCNPNLHFWTTQDEGAAIGLAWIPYFGPAAEGIYTEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDDDDKAGWSHPQFEKGGGSGGGSGGGSWSHPQFEK/SIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSVTKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFT

CDR Sequences (chothia definition)
CDRH1	GASIRGY
CDRH2	HSTGS
CDRH3	GAWNVATVYYYYGMDV
CDRL1	RASQSVSSSYFA
CDRL2	GTSTRAP
CDRL3	QQYGNSLYT

Orientation Angles (from ABangle)
HL	-59.28°
HC1	71.73°
HC2	119.09°
LC1	116.7°
LC2	83.53°
dc	16.95Å

Fv Details
Heavy chain	O
Light chain	R
Heavy subgroup	IGHV4
Light subgroup	IGKV3
Species	HOMO SAPIENS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	100H	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	Q	E	S	G	P	G	L	G	K	P	S	E	T	L	S	L	S	C	T	V	S	G	A	S	I	R	G	Y	F	W	N	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	Y	I	H	S	T	G	S	T	N	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	V	S	L	N	V	N	S	V	T	A	A	D	T	A	V	Y	F	C	A	R	G	A	W	N	V	A	T	V	Y	Y	Y	Y	G	M	D	V	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
E	I	V	L	T	Q	S	P	G	T	L	S	L	S	P	G	E	R	A	T	L	S	C	R	A	S	Q	S	V	S	S	S	Y	F	A	W	Y	Q	Q	K	P	G	Q	A	P	R	L	L	I	S	G	T	S	T	R	A	P	G	I	P	D	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	R	L	E	P	E	D	F	A	V	Y	F	C	Q	Q	Y	G	N	S	L	Y	T	F	G	Q	G	T	K	L	E	I	K

Antigen Details
Antigen chains	B,E
Antigen type	protein
Antigen name	virion spike glycoprotein; virion spike glycoprotein,virion spike glycoprotein,ebolavirus (makona) gp2
Antigen species	ebola virus ; zaire ebolavirus, ebola virus
Antigen sequence	NNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREVIVNAQPKCNPNLHFWTTQDEGAAIGLAWIPYFGPAAEGIYTEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDDDDKAGWSHPQFEKGGGSGGGSGGGSWSHPQFEK/SIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSVTKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFT

CDR Sequences (chothia definition)
CDRH1	GASIRGY
CDRH2	HSTGS
CDRH3	GAWNVATVYYYYGMDV
CDRL1	RASQSVSSSYFA
CDRL2	GTSTRAP
CDRL3	QQYGNSLYT

Orientation Angles (from ABangle)
HL	-58.99°
HC1	72.22°
HC2	118.93°
LC1	116.71°
LC2	83.64°
dc	16.76Å

Fv Details
Heavy chain	N
Light chain	Q
Heavy subgroup	IGHV4
Light subgroup	IGKV3
Species	HOMO SAPIENS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	100H	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	Q	E	S	G	P	G	L	G	K	P	S	E	T	L	S	L	S	C	T	V	S	G	A	S	I	R	G	Y	F	W	N	W	I	R	Q	P	P	G	K	G	L	E	W	I	G	Y	I	H	S	T	G	S	T	N	Y	N	P	S	L	K	S	R	V	T	I	S	V	D	T	S	K	N	Q	V	S	L	N	V	N	S	V	T	A	A	D	T	A	V	Y	F	C	A	R	G	A	W	N	V	A	T	V	Y	Y	Y	Y	G	M	D	V	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
E	I	V	L	T	Q	S	P	G	T	L	S	L	S	P	G	E	R	A	T	L	S	C	R	A	S	Q	S	V	S	S	S	Y	F	A	W	Y	Q	Q	K	P	G	Q	A	P	R	L	L	I	S	G	T	S	T	R	A	P	G	I	P	D	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	R	L	E	P	E	D	F	A	V	Y	F	C	Q	Q	Y	G	N	S	L	Y	T	F	G	Q	G	T	K	L	E	I	K

Antigen Details
Antigen chains	A,D
Antigen type	protein
Antigen name	virion spike glycoprotein; virion spike glycoprotein,virion spike glycoprotein,ebolavirus (makona) gp2
Antigen species	ebola virus ; zaire ebolavirus, ebola virus
Antigen sequence	NNNTHHQDTGEESASSGKLGLITNTIAGVAGLITGGRRTRREVIVNAQPKCNPNLHFWTTQDEGAAIGLAWIPYFGPAAEGIYTEGLMHNQDGLICGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQRWGGTCHILGPDCCIEPHDWTKNITDKIDQIIHDDDDKAGWSHPQFEKGGGSGGGSGGGSWSHPQFEK/SIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSVTKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFT

CDR Sequences (chothia definition)
CDRH1	GASIRGY
CDRH2	HSTGS
CDRH3	GAWNVATVYYYYGMDV
CDRL1	RASQSVSSSYFA
CDRL2	GTSTRAP
CDRL3	QQYGNSLYT

Orientation Angles (from ABangle)
HL	-59.28°
HC1	71.62°
HC2	119.87°
LC1	117.26°
LC2	83.65°
dc	16.93Å

Fv Details
Heavy chain	J
Light chain	M
Heavy subgroup	IGHV3
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	100H	100I	100J	100K	100L	100M	100N	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	V	E	E	S	G	G	G	V	V	Q	P	G	G	S	L	R	L	S	C	A	A	S	G	F	M	F	S	N	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	M	A	F	I	R	Y	D	D	S	K	K	F	Y	A	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	S	L	R	A	E	D	T	A	L	Y	Y	C	A	K	E	L	L	Q	V	Y	T	S	A	W	G	E	G	H	S	Y	Y	Y	A	L	D	V	W	G	L	G	T	A	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	V	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	D	I	S	N	W	L	A	W	Y	Q	Q	K	P	G	K	A	P	E	L	L	I	Y	T	A	S	I	L	Q	S	G	V	S	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	S	A	T	Y	Y	C	Q	Q	G	K	S	F	P	Y	T	F	G	Q	G	T	K	L	E	I	K

Antigen Details
Antigen chains	C
Antigen type	protein
Antigen name	virion spike glycoprotein
Antigen species	EBOLA VIRUS
Antigen sequence	SIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSVTKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFT

CDR Sequences (chothia definition)
CDRH1	GFMFSNY
CDRH2	RYDDSK
CDRH3	ELLQVYTSAWGEGHSYYYALDV
CDRL1	RASQDISNWLA
CDRL2	TASILQS
CDRL3	QQGKSFPYT

Orientation Angles (from ABangle)
HL	-59.44°
HC1	69.09°
HC2	119.31°
LC1	119.85°
LC2	82.29°
dc	16.92Å

Fv Details
Heavy chain	H
Light chain	K
Heavy subgroup	IGHV3
Light subgroup	IGKV1
Species	HOMO SAPIENS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	100H	100I	100J	100K	100L	100M	100N	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	V	E	E	S	G	G	G	V	V	Q	P	G	G	S	L	R	L	S	C	A	A	S	G	F	M	F	S	N	Y	G	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	M	A	F	I	R	Y	D	D	S	K	K	F	Y	A	D	S	V	K	G	R	F	T	I	S	R	D	N	S	K	N	T	L	Y	L	Q	M	N	S	L	R	A	E	D	T	A	L	Y	Y	C	A	K	E	L	L	Q	V	Y	T	S	A	W	G	E	G	H	S	Y	Y	Y	A	L	D	V	W	G	L	G	T	A	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	V	S	A	S	V	G	D	R	V	T	I	T	C	R	A	S	Q	D	I	S	N	W	L	A	W	Y	Q	Q	K	P	G	K	A	P	E	L	L	I	Y	T	A	S	I	L	Q	S	G	V	S	S	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	S	A	T	Y	Y	C	Q	Q	G	K	S	F	P	Y	T	F	G	Q	G	T	K	L	E	I	K

Antigen Details
Antigen chains	A
Antigen type	protein
Antigen name	virion spike glycoprotein
Antigen species	EBOLA VIRUS
Antigen sequence	SIPLGVIHNSTLQVSDVDKLVCRDKLSSTNQLRSVGLNLEGNGVATDVPSVTKRWGFRSGVPPKVVNYEAGEWAENCYNLEIKKPDGSECLPAAPDGIRGFPRCRYVHKVSGTGPCAGDFAFHKEGAFFLYDRLASTVIYRGTTFAEGVVAFLILPQAKKDFFSSHPLREPVNATEDPSSGYYSTTIRYQATGFGTNETEYLFEVDNLTYVQLESRFTPQFLLQLNETIYASGKRSNTTGKLIWKVNPEIDTTIGEWAFWETKKNLTRKIRSEELSFT

CDR Sequences (chothia definition)
CDRH1	GFMFSNY
CDRH2	RYDDSK
CDRH3	ELLQVYTSAWGEGHSYYYALDV
CDRL1	RASQDISNWLA
CDRL2	TASILQS
CDRL3	QQGKSFPYT

Orientation Angles (from ABangle)
HL	-58.83°
HC1	69.77°
HC2	119.71°
LC1	120.3°
LC2	82.06°
dc	16.71Å

Additional links and files for download: see help for more details.

Chothia-numbered structure	Download
IMGT-numbered structure	Download
Non-annotated structure from the PDB	Download
Summary file for this antibody	Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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