Structure Viewer: 7pa6

>   Structure details

Jc Polyomavirus Vp1 in complex with Scfv 27C11

PDB7pa6
SpeciesSYNTHETIC CONSTRUCT
MethodX-RAY DIFFRACTION
Resolution1.9Å
Number of Fvs10
In complexTrue
Light chain typeunknown
Has constant regionFalse
>   Structure visualisation
Please note the WebGL plugin needs to be enabled to use PV Viewer.

Display options:














>   Fv information

This PDB has 10 Fv(s).

>   K/K
Fv Details
Heavy chainK
Light chainK
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsA
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-60.98°
HC172.65°
HC2119.42°
LC1120.58°
LC282.23°
dc16.14Å
>   L/L
Fv Details
Heavy chainL
Light chainL
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsB
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-61.59°
HC172.81°
HC2119.56°
LC1120.85°
LC281.86°
dc16.12Å
>   M/M
Fv Details
Heavy chainM
Light chainM
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsC
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-62.39°
HC172.94°
HC2118.74°
LC1119.51°
LC281.52°
dc16.04Å
>   N/N
Fv Details
Heavy chainN
Light chainN
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsD
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-61.23°
HC173.11°
HC2120.03°
LC1121.39°
LC281.95°
dc16.1Å
>   O/O
Fv Details
Heavy chainO
Light chainO
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsE
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-62.29°
HC173.4°
HC2119.64°
LC1120.23°
LC281.46°
dc16.05Å
>   P/P
Fv Details
Heavy chainP
Light chainP
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsF
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-61.72°
HC173.0°
HC2118.88°
LC1120.33°
LC281.99°
dc16.01Å
>   Q/Q
Fv Details
Heavy chainQ
Light chainQ
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsG
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-62.24°
HC173.48°
HC2119.79°
LC1121.07°
LC281.98°
dc16.04Å
>   R/R
Fv Details
Heavy chainR
Light chainR
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsH
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-62.08°
HC173.58°
HC2119.4°
LC1120.47°
LC281.49°
dc16.02Å
>   S/S
Fv Details
Heavy chainS
Light chainS
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsI
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-61.05°
HC172.49°
HC2119.27°
LC1120.7°
LC282.26°
dc16.09Å
>   T/T
Fv Details
Heavy chainT
Light chainT
Heavy subgroupunknown
Light subgroupunknown
SpeciesSYNTHETIC CONSTRUCT
In complex?True
scFv?True
Has constant domain?False

Numbered Sequences (chothia)

Heavy chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 31A 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 82A 82B 82C 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 100A 100B 100C 100D 100E 100F 100G 100H 100I 100J 101 102 103 104 105 106 107 108 109 110 111 112 113
Q V Q L Q E S G P G L V K P S G T L S L T C A V S G D S I S S S N W W S W V R Q P P G K G L E W I G E I Y H S G G T K Y N P S L K S R V T I S V D K S K N H F S L K L R S V T A A D T A V Y Y C A R N R W F D N N R G G Y Y Y Y G M D V W G Q G T T V T V S S

Light chain

1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107
D I Q M T Q S P S S L S A S V G D R V T I T C R A S Q G I S S Y L N W Y Q Q K P G K A P K L L I S A T S D L Q S G V P S R F S G S G S G T D F T L T I S S L Q P E D F A T Y Y C Q Q S Y S T P Y T F G Q G T K L E I K

Antigen Details
Antigen chainsJ
Antigen typeprotein
Antigen nameunknown
Antigen speciesSYNTHETIC CONSTRUCT
Antigen sequenceGSHMGGVEVLEVKTGVDSITEVECFLTPEMGDPDEHLRGFSKSISISDTFESDSPNRDMLPCYSVARIPLPNLNEDLTCGNILMWEAVTLKTEVIGVTSLMNVHSNGQATHDNGAGKPVQGTSFHFFSVGGEALELQGVLFNYRTKYPDGTIFPKNATVQSQVMNTEHKAYLDKNKAYPVECWVPDPTRNENTRYFGTLTGGENVPPVLHITNTATTVLLDEFGVGPLCKGDNLYLSAVDVCGMFTNRSGSQQWRGLSRYFKVQLRKRRVKN

CDR Sequences (chothia definition)
CDRH1GDSISSSN
CDRH2YHSGG
CDRH3NRWFDNNRGGYYYYGMDV
CDRL1RASQGISSYLN
CDRL2ATSDLQS
CDRL3QQSYSTPYT

Orientation Angles (from ABangle)
HL-61.6°
HC172.59°
HC2119.68°
LC1121.47°
LC282.27°
dc16.16Å
>   Downloads

Additional links and files for download: see help for more details.

Chothia-numbered structure Download
IMGT-numbered structure Download
Non-annotated structure from the PDB Download
Summary file for this antibody Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

Our privacy policy