Pfcyrpa Bound to Fab Fragments From Monoclonal antibodies Cy.003, Cy.004 and Cy.007
| PDB | 7pi3 |
| Species | GALLUS GALLUS |
| Method | X-RAY DIFFRACTION |
| Resolution | 3.269Å |
| Number of Fvs | 12 |
| In complex | True |
| Light chain type | unknown |
| Has constant region | True |
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Display options: |
This PDB has 12 Fv(s).
| Fv Details | |
|---|---|
| Heavy chain | T |
| Light chain | U |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
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| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | A | S | G | F | D | F | S | S | Y | A | M | G | W | V | R | Q | A | P | G | K | G | L | E | Y | V | A | G | I | R | N | D | G | S | F | T | L | Y | T | P | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | A | T | Y | F | C | T | K | S | A | D | D | G | G | H | Y | S | D | F | S | G | E | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
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| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | S | T | Y | N | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | Y | N | D | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | Y | C | G | N | S | D | S | R | N | V | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | O |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFDFSSY |
| CDRH2 | RNDGSF |
| CDRH3 | SADDGGHYSDFSGEIDA |
| CDRL1 | SGSTYNYG |
| CDRL2 | YNDKRPS |
| CDRL3 | GNSDSRNVA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -50.06° |
| HC1 | 66.73° |
| HC2 | 115.65° |
| LC1 | 114.81° |
| LC2 | 88.51° |
| dc | 15.98Å |
| Fv Details | |
|---|---|
| Heavy chain | W |
| Light chain | X |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 31A | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | G | S | G | F | F | S | F | S | S | Y | T | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | S | I | S | S | G | G | G | T | N | Y | G | A | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | L | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | H | G | V | N | G | C | D | W | S | Y | S | V | G | C | V | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
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| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | S | Y | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | L | I | Y | N | N | Q | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | F | C | G | S | R | D | N | S | G | G | I | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | V |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFFSFSSY |
| CDRH2 | SSGGG |
| CDRH3 | HGVNGCDWSYSVGCVDA |
| CDRL1 | SGGSSSYYG |
| CDRL2 | NNQKRPS |
| CDRL3 | GSRDNSGGI |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -50.06° |
| HC1 | 70.05° |
| HC2 | 117.03° |
| LC1 | 113.18° |
| LC2 | 90.38° |
| dc | 15.47Å |
| Fv Details | |
|---|---|
| Heavy chain | R |
| Light chain | S |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
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| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | T | L | S | L | V | C | K | G | S | G | F | T | F | S | S | Y | E | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | D | I | C | I | G | G | S | Y | T | G | Y | G | P | A | V | K | G | R | A | T | I | S | R | D | D | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | T | A | R | S | D | Y | C | I | T | G | L | D | D | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
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| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | D | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | E | N | N | K | R | P | S | D | I | P | S | R | F | S | G | S | K | F | G | S | T | H | T | L | T | I | T | G | V | Q | A | D | D | E | A | V | Y | F | C | G | S | R | D | T | N | N | G | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | O |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFTFSSY |
| CDRH2 | CIGGSY |
| CDRH3 | TARSDYCITGLDDIDA |
| CDRL1 | SGGSSDYG |
| CDRL2 | ENNKRPS |
| CDRL3 | GSRDTNNGA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -52.77° |
| HC1 | 68.55° |
| HC2 | 117.02° |
| LC1 | 116.42° |
| LC2 | 88.0° |
| dc | 15.95Å |
| Fv Details | |
|---|---|
| Heavy chain | P |
| Light chain | Q |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 31A | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
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| V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | G | S | G | F | F | S | F | S | S | Y | T | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | S | I | S | S | G | G | G | T | N | Y | G | A | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | L | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | H | G | V | N | G | C | D | W | S | Y | S | V | G | C | V | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
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| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | S | Y | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | L | I | Y | N | N | Q | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | F | C | G | S | R | D | N | S | G | G | I | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | O |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFFSFSSY |
| CDRH2 | SSGGG |
| CDRH3 | HGVNGCDWSYSVGCVDA |
| CDRL1 | SGGSSSYYG |
| CDRL2 | NNQKRPS |
| CDRL3 | GSRDNSGGI |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -49.78° |
| HC1 | 69.64° |
| HC2 | 117.0° |
| LC1 | 113.77° |
| LC2 | 90.2° |
| dc | 15.5Å |
| Fv Details | |
|---|---|
| Heavy chain | K |
| Light chain | L |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | T | L | S | L | V | C | K | G | S | G | F | T | F | S | S | Y | E | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | D | I | C | I | G | G | S | Y | T | G | Y | G | P | A | V | K | G | R | A | T | I | S | R | D | D | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | T | A | R | S | D | Y | C | I | T | G | L | D | D | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | D | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | E | N | N | K | R | P | S | D | I | P | S | R | F | S | G | S | K | F | G | S | T | H | T | L | T | I | T | G | V | Q | A | D | D | E | A | V | Y | F | C | G | S | R | D | T | N | N | G | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | H |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFTFSSY |
| CDRH2 | CIGGSY |
| CDRH3 | TARSDYCITGLDDIDA |
| CDRL1 | SGGSSDYG |
| CDRL2 | ENNKRPS |
| CDRL3 | GSRDTNNGA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -53.02° |
| HC1 | 68.33° |
| HC2 | 117.27° |
| LC1 | 117.07° |
| LC2 | 89.29° |
| dc | 16.04Å |
| Fv Details | |
|---|---|
| Heavy chain | B |
| Light chain | C |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 31A | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | G | S | G | F | F | S | F | S | S | Y | T | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | S | I | S | S | G | G | G | T | N | Y | G | A | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | L | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | H | G | V | N | G | C | D | W | S | Y | S | V | G | C | V | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | S | Y | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | L | I | Y | N | N | Q | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | F | C | G | S | R | D | N | S | G | G | I | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | A |
| Antigen type | protein |
| Antigen name | monoclonal antibody cy.004 heavy chain |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFFSFSSY |
| CDRH2 | SSGGG |
| CDRH3 | HGVNGCDWSYSVGCVDA |
| CDRL1 | SGGSSSYYG |
| CDRL2 | NNQKRPS |
| CDRL3 | GSRDNSGGI |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -49.9° |
| HC1 | 68.99° |
| HC2 | 117.63° |
| LC1 | 114.77° |
| LC2 | 89.35° |
| dc | 15.56Å |
| Fv Details | |
|---|---|
| Heavy chain | M |
| Light chain | N |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | A | S | G | F | D | F | S | S | Y | A | M | G | W | V | R | Q | A | P | G | K | G | L | E | Y | V | A | G | I | R | N | D | G | S | F | T | L | Y | T | P | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | A | T | Y | F | C | T | K | S | A | D | D | G | G | H | Y | S | D | F | S | G | E | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | S | T | Y | N | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | Y | N | D | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | Y | C | G | N | S | D | S | R | N | V | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | H |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFDFSSY |
| CDRH2 | RNDGSF |
| CDRH3 | SADDGGHYSDFSGEIDA |
| CDRL1 | SGSTYNYG |
| CDRL2 | YNDKRPS |
| CDRL3 | GNSDSRNVA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -48.91° |
| HC1 | 67.32° |
| HC2 | 116.89° |
| LC1 | 115.65° |
| LC2 | 89.27° |
| dc | 15.92Å |
| Fv Details | |
|---|---|
| Heavy chain | Y |
| Light chain | Z |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | T | L | S | L | V | C | K | G | S | G | F | T | F | S | S | Y | E | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | D | I | C | I | G | G | S | Y | T | G | Y | G | P | A | V | K | G | R | A | T | I | S | R | D | D | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | T | A | R | S | D | Y | C | I | T | G | L | D | D | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | D | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | E | N | N | K | R | P | S | D | I | P | S | R | F | S | G | S | K | F | G | S | T | H | T | L | T | I | T | G | V | Q | A | D | D | E | A | V | Y | F | C | G | S | R | D | T | N | N | G | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | V |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFTFSSY |
| CDRH2 | CIGGSY |
| CDRH3 | TARSDYCITGLDDIDA |
| CDRL1 | SGGSSDYG |
| CDRL2 | ENNKRPS |
| CDRL3 | GSRDTNNGA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -52.5° |
| HC1 | 68.11° |
| HC2 | 117.22° |
| LC1 | 117.32° |
| LC2 | 87.92° |
| dc | 16.15Å |
| Fv Details | |
|---|---|
| Heavy chain | a |
| Light chain | b |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | A | S | G | F | D | F | S | S | Y | A | M | G | W | V | R | Q | A | P | G | K | G | L | E | Y | V | A | G | I | R | N | D | G | S | F | T | L | Y | T | P | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | A | T | Y | F | C | T | K | S | A | D | D | G | G | H | Y | S | D | F | S | G | E | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | S | T | Y | N | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | Y | N | D | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | Y | C | G | N | S | D | S | R | N | V | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | V |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFDFSSY |
| CDRH2 | RNDGSF |
| CDRH3 | SADDGGHYSDFSGEIDA |
| CDRL1 | SGSTYNYG |
| CDRL2 | YNDKRPS |
| CDRL3 | GNSDSRNVA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -51.51° |
| HC1 | 67.0° |
| HC2 | 116.6° |
| LC1 | 114.57° |
| LC2 | 87.06° |
| dc | 15.89Å |
| Fv Details | |
|---|---|
| Heavy chain | I |
| Light chain | J |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 31A | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | G | S | G | F | F | S | F | S | S | Y | T | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | S | I | S | S | G | G | G | T | N | Y | G | A | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | L | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | H | G | V | N | G | C | D | W | S | Y | S | V | G | C | V | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | S | Y | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | L | I | Y | N | N | Q | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | F | C | G | S | R | D | N | S | G | G | I | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | H |
| Antigen type | protein |
| Antigen name | cysteine-rich protective antigen |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFFSFSSY |
| CDRH2 | SSGGG |
| CDRH3 | HGVNGCDWSYSVGCVDA |
| CDRL1 | SGGSSSYYG |
| CDRL2 | NNQKRPS |
| CDRL3 | GSRDNSGGI |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -50.3° |
| HC1 | 69.38° |
| HC2 | 117.06° |
| LC1 | 113.63° |
| LC2 | 89.33° |
| dc | 15.39Å |
| Fv Details | |
|---|---|
| Heavy chain | D |
| Light chain | E |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | T | L | S | L | V | C | K | G | S | G | F | T | F | S | S | Y | E | M | Q | W | V | R | Q | A | P | G | K | G | L | E | W | V | A | D | I | C | I | G | G | S | Y | T | G | Y | G | P | A | V | K | G | R | A | T | I | S | R | D | D | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | G | T | Y | Y | C | A | K | T | A | R | S | D | Y | C | I | T | G | L | D | D | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | G | S | S | D | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | E | N | N | K | R | P | S | D | I | P | S | R | F | S | G | S | K | F | G | S | T | H | T | L | T | I | T | G | V | Q | A | D | D | E | A | V | Y | F | C | G | S | R | D | T | N | N | G | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | A |
| Antigen type | protein |
| Antigen name | monoclonal antibody cy.004 heavy chain |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFTFSSY |
| CDRH2 | CIGGSY |
| CDRH3 | TARSDYCITGLDDIDA |
| CDRL1 | SGGSSDYG |
| CDRL2 | ENNKRPS |
| CDRL3 | GSRDTNNGA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -53.5° |
| HC1 | 68.87° |
| HC2 | 117.0° |
| LC1 | 116.4° |
| LC2 | 87.76° |
| dc | 15.85Å |
| Fv Details | |
|---|---|
| Heavy chain | F |
| Light chain | G |
| Heavy subgroup | unknown |
| Light subgroup | unknown |
| Species | GALLUS GALLUS |
| In complex? | True |
| scFv? | False |
| Has constant domain? | True |
| Numbered Sequences (chothia) |
|---|
Heavy chain
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 52A | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 82A | 82B | 82C | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 100A | 100B | 100C | 100D | 100E | 100F | 100G | 100H | 100I | 101 | 102 | 103 | 104 | 105 | 106 | 107 | 108 | 109 | 110 | 111 | 112 | 113 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | V | T | L | D | E | S | G | G | G | L | Q | T | P | G | G | A | L | S | L | V | C | K | A | S | G | F | D | F | S | S | Y | A | M | G | W | V | R | Q | A | P | G | K | G | L | E | Y | V | A | G | I | R | N | D | G | S | F | T | L | Y | T | P | A | V | K | G | R | A | T | I | S | R | D | N | G | Q | S | T | V | R | L | Q | L | N | N | L | R | A | E | D | T | A | T | Y | F | C | T | K | S | A | D | D | G | G | H | Y | S | D | F | S | G | E | I | D | A | W | G | H | G | T | E | V | I | V | S | S |
Light chain
| 3 | 4 | 5 | 6 | 7 | 8 | 9 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 34 | 35 | 36 | 37 | 38 | 39 | 39A | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | 100 | 101 | 102 | 103 | 104 | 105 | 106 | 107 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A | L | T | Q | P | S | S | V | S | A | N | P | G | E | T | V | K | I | T | C | S | G | S | T | Y | N | Y | G | W | Y | Q | Q | K | S | P | G | S | A | P | V | T | V | I | Y | Y | N | D | K | R | P | S | D | I | P | S | R | F | S | G | S | K | S | G | S | T | G | T | L | T | I | T | G | V | Q | A | E | D | E | A | V | Y | Y | C | G | N | S | D | S | R | N | V | A | F | G | A | G | T | T | L | T | V | L |
| Antigen Details | |
|---|---|
| Antigen chains | A |
| Antigen type | protein |
| Antigen name | monoclonal antibody cy.004 heavy chain |
| Antigen species | PLASMODIUM FALCIPARUM 3D7 |
| Antigen sequence | DSRHVFIRTELSFIKNNVPCIRDMFFIYKRELYNICLDDLKGEEDETHIYVQKKVKDSWITLNDLFKETDLTGRPHIFAYVDVEEIIILLCEDEEFSNRKKDMTCHRFYSNDGKEYNNAEITISDYILKDKLLSSYVSLPLKIENREYFLICGVSPYKFKDDNKKDDILCMASHDKGETWGTKIVIKYDNYKLGVQYFFLRPYISKNDLSFHFYVGDNINNVKNVNFIECTHEKDLEFVCSNRDFLKDNKVLQDVSTLNDEYIVSYGNDNNFAECYIFFNNENSILIKPEKYGNTAAGCYGGTFVKIDENRALFIYSSSQGIYNIHTIYYANYEGGGGSEPEA |
| CDR Sequences (chothia definition) | |
|---|---|
| CDRH1 | GFDFSSY |
| CDRH2 | RNDGSF |
| CDRH3 | SADDGGHYSDFSGEIDA |
| CDRL1 | SGSTYNYG |
| CDRL2 | YNDKRPS |
| CDRL3 | GNSDSRNVA |
| Orientation Angles (from ABangle) | |
|---|---|
| HL | -49.37° |
| HC1 | 66.89° |
| HC2 | 116.29° |
| LC1 | 115.69° |
| LC2 | 88.43° |
| dc | 15.88Å |
Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]
SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]
Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]
