Structure Viewer: 7uja

> Structure details

Cryo-Em Structure of Human Respiratory Syncytial Virus F Variant (Construct Pxcs847a)

PDB	7uja
Species	MUS MUSCULUS
Method	ELECTRON MICROSCOPY
Resolution	0Å
Number of Fvs	6
In complex	True
Light chain type	Kappa
Has constant region	True

> Fv information

This PDB has 6 Fv(s).

Fv Details
Heavy chain	B
Light chain	D
Heavy subgroup	IGHV3
Light subgroup	IGKV1
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	S	F	S	H	Y	A	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	S	Y	D	G	E	N	T	Y	Y	A	D	S	V	K	G	R	F	S	I	S	R	D	N	S	K	N	T	V	S	L	Q	M	N	S	L	R	P	E	D	T	A	L	Y	Y	C	A	R	D	R	I	V	D	D	Y	Y	Y	Y	G	M	D	V	W	G	Q	G	A	T	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	95A	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	Q	A	S	Q	D	I	K	K	Y	L	N	W	Y	H	Q	K	P	G	K	V	P	E	L	L	M	H	D	A	S	N	L	E	T	G	V	P	S	R	F	S	G	R	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	I	G	T	Y	Y	C	Q	Q	Y	D	N	L	P	P	L	T	F	G	G	G	T	K	V	E	I	K

Antigen Details
Antigen chains	A
Antigen type	protein
Antigen name	rsv variant (construct pxcs847a) f1
Antigen species	RESPIRATORY SYNCYTIAL VIRUS
Antigen sequence	FLGFLLGVGSACASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTIKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNIDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSSEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGG

CDR Sequences (chothia definition)
CDRH1	GFSFSHY
CDRH2	SYDGEN
CDRH3	DRIVDDYYYYGMDV
CDRL1	QASQDIKKYLN
CDRL2	DASNLET
CDRL3	QQYDNLPPLT

Orientation Angles (from ABangle)
HL	-60.56°
HC1	71.56°
HC2	121.78°
LC1	121.13°
LC2	80.87°
dc	17.21Å

Fv Details
Heavy chain	E
Light chain	F
Heavy subgroup	IGHV1
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	V	Q	S	G	A	E	V	K	K	P	G	A	T	V	K	V	S	C	K	I	S	G	H	T	L	I	K	L	S	I	H	W	V	R	Q	A	P	G	K	G	L	E	W	M	G	G	Y	E	G	E	V	D	E	I	F	Y	A	Q	K	F	Q	H	R	L	T	V	I	A	D	T	A	T	D	T	V	Y	M	E	L	G	R	L	T	S	D	D	T	A	V	Y	F	C	G	T	L	G	V	T	V	T	E	A	G	L	G	I	D	D	Y	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
E	I	V	L	T	Q	S	P	G	T	L	S	L	S	P	G	E	R	A	T	L	S	C	R	A	S	Q	I	V	S	R	N	H	L	A	W	Y	Q	Q	K	P	G	Q	A	P	R	L	L	I	F	G	A	S	S	R	A	T	G	I	P	V	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	N	G	L	A	P	E	D	F	A	V	Y	Y	C	L	S	S	D	S	S	I	F	T	F	G	P	G	T	K	V	D	F	K

Antigen Details
Antigen chains	A,P
Antigen type	protein
Antigen name	rsv variant (construct pxcs847a) f1; rsv variant (construct pxcs847a) f2
Antigen species	RESPIRATORY SYNCYTIAL VIRUS
Antigen sequence	MELPILKTNAITTILAAVTLCFASSQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPACNSRARR/FLGFLLGVGSACASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTIKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNIDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSSEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGG

CDR Sequences (chothia definition)
CDRH1	GHTLIKL
CDRH2	EGEVDE
CDRH3	LGVTVTEAGLGIDDY
CDRL1	RASQIVSRNHLA
CDRL2	GASSRAT
CDRL3	LSSDSSIFT

Orientation Angles (from ABangle)
HL	-56.48°
HC1	70.64°
HC2	119.52°
LC1	122.71°
LC2	83.41°
dc	16.94Å

Fv Details
Heavy chain	G
Light chain	H
Heavy subgroup	IGHV3
Light subgroup	IGKV1
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	S	F	S	H	Y	A	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	S	Y	D	G	E	N	T	Y	Y	A	D	S	V	K	G	R	F	S	I	S	R	D	N	S	K	N	T	V	S	L	Q	M	N	S	L	R	P	E	D	T	A	L	Y	Y	C	A	R	D	R	I	V	D	D	Y	Y	Y	Y	G	M	D	V	W	G	Q	G	A	T	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	95A	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	Q	A	S	Q	D	I	K	K	Y	L	N	W	Y	H	Q	K	P	G	K	V	P	E	L	L	M	H	D	A	S	N	L	E	T	G	V	P	S	R	F	S	G	R	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	I	G	T	Y	Y	C	Q	Q	Y	D	N	L	P	P	L	T	F	G	G	G	T	K	V	E	I	K

Antigen Details
Antigen chains	K
Antigen type	protein
Antigen name	rsv variant (construct pxcs847a) f1
Antigen species	RESPIRATORY SYNCYTIAL VIRUS
Antigen sequence	FLGFLLGVGSACASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTIKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNIDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSSEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGG

CDR Sequences (chothia definition)
CDRH1	GFSFSHY
CDRH2	SYDGEN
CDRH3	DRIVDDYYYYGMDV
CDRL1	QASQDIKKYLN
CDRL2	DASNLET
CDRL3	QQYDNLPPLT

Orientation Angles (from ABangle)
HL	-60.68°
HC1	71.61°
HC2	121.84°
LC1	120.96°
LC2	80.71°
dc	17.15Å

Fv Details
Heavy chain	I
Light chain	J
Heavy subgroup	IGHV1
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	V	Q	S	G	A	E	V	K	K	P	G	A	T	V	K	V	S	C	K	I	S	G	H	T	L	I	K	L	S	I	H	W	V	R	Q	A	P	G	K	G	L	E	W	M	G	G	Y	E	G	E	V	D	E	I	F	Y	A	Q	K	F	Q	H	R	L	T	V	I	A	D	T	A	T	D	T	V	Y	M	E	L	G	R	L	T	S	D	D	T	A	V	Y	F	C	G	T	L	G	V	T	V	T	E	A	G	L	G	I	D	D	Y	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
E	I	V	L	T	Q	S	P	G	T	L	S	L	S	P	G	E	R	A	T	L	S	C	R	A	S	Q	I	V	S	R	N	H	L	A	W	Y	Q	Q	K	P	G	Q	A	P	R	L	L	I	F	G	A	S	S	R	A	T	G	I	P	V	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	N	G	L	A	P	E	D	F	A	V	Y	Y	C	L	S	S	D	S	S	I	F	T	F	G	P	G	T	K	V	D	F	K

Antigen Details
Antigen chains	K,R
Antigen type	protein
Antigen name	rsv variant (construct pxcs847a) f1; rsv variant (construct pxcs847a) f2
Antigen species	RESPIRATORY SYNCYTIAL VIRUS
Antigen sequence	MELPILKTNAITTILAAVTLCFASSQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPACNSRARR/FLGFLLGVGSACASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTIKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNIDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSSEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGG

CDR Sequences (chothia definition)
CDRH1	GHTLIKL
CDRH2	EGEVDE
CDRH3	LGVTVTEAGLGIDDY
CDRL1	RASQIVSRNHLA
CDRL2	GASSRAT
CDRL3	LSSDSSIFT

Orientation Angles (from ABangle)
HL	-56.59°
HC1	70.66°
HC2	119.57°
LC1	122.92°
LC2	83.14°
dc	16.96Å

Fv Details
Heavy chain	L
Light chain	M
Heavy subgroup	IGHV3
Light subgroup	IGKV1
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	101	102	103	104	105	106	107	108	109	110	111	112	113
E	V	Q	L	V	E	S	G	G	G	V	V	Q	P	G	R	S	L	R	L	S	C	A	A	S	G	F	S	F	S	H	Y	A	M	H	W	V	R	Q	A	P	G	K	G	L	E	W	V	A	V	I	S	Y	D	G	E	N	T	Y	Y	A	D	S	V	K	G	R	F	S	I	S	R	D	N	S	K	N	T	V	S	L	Q	M	N	S	L	R	P	E	D	T	A	L	Y	Y	C	A	R	D	R	I	V	D	D	Y	Y	Y	Y	G	M	D	V	W	G	Q	G	A	T	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	95A	96	97	98	99	100	101	102	103	104	105	106	107
D	I	Q	M	T	Q	S	P	S	S	L	S	A	S	V	G	D	R	V	T	I	T	C	Q	A	S	Q	D	I	K	K	Y	L	N	W	Y	H	Q	K	P	G	K	V	P	E	L	L	M	H	D	A	S	N	L	E	T	G	V	P	S	R	F	S	G	R	G	S	G	T	D	F	T	L	T	I	S	S	L	Q	P	E	D	I	G	T	Y	Y	C	Q	Q	Y	D	N	L	P	P	L	T	F	G	G	G	T	K	V	E	I	K

Antigen Details
Antigen chains	C
Antigen type	protein
Antigen name	rsv variant (construct pxcs847a) f1
Antigen species	RESPIRATORY SYNCYTIAL VIRUS
Antigen sequence	FLGFLLGVGSACASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTIKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNIDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSSEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGG

CDR Sequences (chothia definition)
CDRH1	GFSFSHY
CDRH2	SYDGEN
CDRH3	DRIVDDYYYYGMDV
CDRL1	QASQDIKKYLN
CDRL2	DASNLET
CDRL3	QQYDNLPPLT

Orientation Angles (from ABangle)
HL	-60.42°
HC1	71.65°
HC2	121.79°
LC1	121.11°
LC2	80.96°
dc	17.23Å

Fv Details
Heavy chain	N
Light chain	O
Heavy subgroup	IGHV1
Light subgroup	IGKV3
Species	MUS MUSCULUS
In complex?	True
scFv?	False
Has constant domain?	True

Numbered Sequences (chothia)

Heavy chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	52A	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	82A	82B	82C	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	100A	100B	100C	100D	100E	100F	100G	101	102	103	104	105	106	107	108	109	110	111	112	113
Q	V	Q	L	V	Q	S	G	A	E	V	K	K	P	G	A	T	V	K	V	S	C	K	I	S	G	H	T	L	I	K	L	S	I	H	W	V	R	Q	A	P	G	K	G	L	E	W	M	G	G	Y	E	G	E	V	D	E	I	F	Y	A	Q	K	F	Q	H	R	L	T	V	I	A	D	T	A	T	D	T	V	Y	M	E	L	G	R	L	T	S	D	D	T	A	V	Y	F	C	G	T	L	G	V	T	V	T	E	A	G	L	G	I	D	D	Y	W	G	Q	G	T	L	V	T	V	S	S

Light chain

1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25	26	27	28	29	30	30A	31	32	33	34	35	36	37	38	39	40	41	42	43	44	45	46	47	48	49	50	51	52	53	54	55	56	57	58	59	60	61	62	63	64	65	66	67	68	69	70	71	72	73	74	75	76	77	78	79	80	81	82	83	84	85	86	87	88	89	90	91	92	93	94	95	96	97	98	99	100	101	102	103	104	105	106	107
E	I	V	L	T	Q	S	P	G	T	L	S	L	S	P	G	E	R	A	T	L	S	C	R	A	S	Q	I	V	S	R	N	H	L	A	W	Y	Q	Q	K	P	G	Q	A	P	R	L	L	I	F	G	A	S	S	R	A	T	G	I	P	V	R	F	S	G	S	G	S	G	T	D	F	T	L	T	I	N	G	L	A	P	E	D	F	A	V	Y	Y	C	L	S	S	D	S	S	I	F	T	F	G	P	G	T	K	V	D	F	K

Antigen Details
Antigen chains	C,Q
Antigen type	protein
Antigen name	rsv variant (construct pxcs847a) f1; rsv variant (construct pxcs847a) f2
Antigen species	RESPIRATORY SYNCYTIAL VIRUS
Antigen sequence	MELPILKTNAITTILAAVTLCFASSQNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPACNSRARR/FLGFLLGVGSACASGIAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTIKVLDLKNYIDKQLLPIVNKQSCSISNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLPSEVNLCNIDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTLYYVNKQEGKSLYVKGEPIINFYDPLVFPSSEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGEWVLLSTFLGG

CDR Sequences (chothia definition)
CDRH1	GHTLIKL
CDRH2	EGEVDE
CDRH3	LGVTVTEAGLGIDDY
CDRL1	RASQIVSRNHLA
CDRL2	GASSRAT
CDRL3	LSSDSSIFT

Orientation Angles (from ABangle)
HL	-56.72°
HC1	70.42°
HC2	119.62°
LC1	122.86°
LC2	83.05°
dc	16.96Å

Additional links and files for download: see help for more details.

Chothia-numbered structure	Download
IMGT-numbered structure	Download
Non-annotated structure from the PDB	Download
Summary file for this antibody	Download

Schneider, C., Raybould, M.I.J., Deane, C.M. (2022) SAbDab in the Age of Biotherapeutics: Updates including SAbDab-Nano, the Nanobody Structure Tracker. Nucleic Acids Res. 50(D1):D1368-D1372 [link]

SAbDab paper: Dunbar, J., Krawczyk, K. et al (2014). Nucleic Acids Res. 42. D1140-D1146 [link]

Thera-SAbDab paper: Raybould, M.I.J., Marks, C. et al (2019). Nucleic Acids Res. gkz827 [link]

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