TCR Details:

Item	Info
VB chain	E
VA chain	D
VB IMGT details	TRBV12/TRBJ2
VA IMGT details	TRAV12/TRAJ12
Species	human

Antigen Details:

Item	Info
Antigen Chain	C
Antigen Type	Peptide
Antigen Organism	HOMO SAPIENS
Antigen Sequence	RQWGPDPAAV
Antigen Length	10

MHC details:

Item	Info
MHC Chain	A | B
MHC Type	MH1
MHC Species	human
MHC IMGT details	HLA-A*0201

Numbered sequence

Chain type	Chain ID	FASTA/Annotation file	IMGT numbered sequence (Framework/CDR)
VB	E	FASTA file	B2 B3 B4 B5 B6 B7 B8 B9 A G V I Q S P R B10 B11 B12 B13 B14 B15 B16 B17 H E V T E M G Q B18 B19 B20 B21 B22 B23 B24 B25 Q V T L R C K P B26 B27 B28 B29 B37 B38 B39 B40 I S G H D Y L F B41 B42 B43 B44 B45 B46 B47 B48 W Y R Q T M M R B49 B50 B51 B52 B53 B54 B55 B56 G L E L L I Y F B57 B58 B63 B64 B65 B66 B67 B68 N N N V P I D D B69 B70 B71 B72 B73 B74 B75 B76 S G M P E D R F B77 B78 B79 B80 B81 B83 B84 B85 S A K M P N A S B86 B87 B88 B89 B90 B91 B92 B93 F S T L K I Q P B94 B95 B96 B97 B98 B99 B100 B101 S E P R D S A V B102 B103 B104 B105 B106 B107 B108 B109 Y F C A S S L W B110 B111 B112A B112 B113 B114 B115 B116 E K L A K N I Q B117 B118 B119 B120 B121 B122 B123 B124 Y F G A G T R L B125 B126 B127 S V L
VA	D	FASTA file	A2 A3 A4 A5 A6 A7 A8 A9 A E V E Q D P G A10 A11 A12 A13 A14 A15 A16 A17 P L S V P E G A A18 A19 A20 A21 A22 A23 A24 A25 I V S L N C T Y A26 A27 A28 A29 A36 A37 A38 A39 S N S A F Q Y F A40 A41 A42 A43 A44 A45 A46 A47 M W Y R Q Y S R A48 A49 A50 A51 A52 A53 A54 A55 K G P E L L M Y A56 A57 A58 A63 A64 A65 A66 A67 T Y S S G N K E A68 A74 A75 A76 A77 A78 A79 A80 D G R F T A Q V A81 A82 A83 A84 A85 A86 A87 A88 D K S S K Y I S A89 A90 A91 A92 A93 A94 A95 A96 L F I R D S Q P A97 A98 A99 A100 A101 A102 A103 A104 S D S A T Y L C A105 A106 A107 A108 A109 A110 A113 A114 A M R G D S S Y A115 A116 A117 A118 A119 A120 A121 A122 K L I F G S G T A123 A124 A125 A126 A127 A128 R L L V R P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLWEKLAKNIQY	None	14
CDRB2	FNNNVP	None	6
CDRB1	SGHDY	None	5
CDRA3	AMRGDSSYKLI	None	11
CDRA2	TYSSGN	A2-6-B	6
CDRA1	NSAFQY	None	6

Orientation and docking angles:

Angle	Value
BC2	111.93°
BC1	80.00°
BA	-60.13°
AC2	80.39°
AC1	121.87°
dc	15.78Å
Docking angle	44.16°

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
5c07_ED	112.10°	80.10°	-60.76°	80.35°	122.08°	15.77Å	0.7
5c0b_JI	112.28°	80.10°	-60.73°	80.73°	121.94°	15.83Å	0.8
5c0c_ED	112.16°	79.79°	-60.27°	81.04°	122.31°	15.89Å	0.9
5c0a_JI	110.98°	79.72°	-61.04°	79.90°	122.30°	15.78Å	1.5
5c0c_JI	111.80°	79.68°	-60.41°	81.66°	122.42°	15.89Å	1.5

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	4.4
3cvh_QR	113.65°	77.38°	-59.58°	79.78°	118.82°	15.93Å	4.5
4jkp_HL	113.93°	77.37°	-58.92°	82.11°	124.47°	15.16Å	4.7
3u7y_HL	113.61°	76.93°	-60.36°	81.15°	125.35°	15.13Å	5.0
2dlf_HL	110.76°	78.47°	-60.69°	79.06°	117.44°	15.78Å	5.0

TCR Details:

Item	Info
VB chain	J
VA chain	I
VB IMGT details	TRBV12/TRBJ2
VA IMGT details	TRAV12/TRAJ12
Species	human

Antigen Details:

Item	Info
Antigen Chain	H
Antigen Type	Peptide
Antigen Organism	HOMO SAPIENS
Antigen Sequence	RQWGPDPAAV
Antigen Length	10

MHC details:

Item	Info
MHC Chain	F | G
MHC Type	MH1
MHC Species	human
MHC IMGT details	HLA-A*0201

Numbered sequence

Chain type	Chain ID	FASTA/Annotation file	IMGT numbered sequence (Framework/CDR)
VB	J	FASTA file	B2 B3 B4 B5 B6 B7 B8 B9 A G V I Q S P R B10 B11 B12 B13 B14 B15 B16 B17 H E V T E M G Q B18 B19 B20 B21 B22 B23 B24 B25 Q V T L R C K P B26 B27 B28 B29 B37 B38 B39 B40 I S G H D Y L F B41 B42 B43 B44 B45 B46 B47 B48 W Y R Q T M M R B49 B50 B51 B52 B53 B54 B55 B56 G L E L L I Y F B57 B58 B63 B64 B65 B66 B67 B68 N N N V P I D D B69 B70 B71 B72 B73 B74 B75 B76 S G M P E D R F B77 B78 B79 B80 B81 B83 B84 B85 S A K M P N A S B86 B87 B88 B89 B90 B91 B92 B93 F S T L K I Q P B94 B95 B96 B97 B98 B99 B100 B101 S E P R D S A V B102 B103 B104 B105 B106 B107 B108 B109 Y F C A S S L W B110 B111 B112A B112 B113 B114 B115 B116 E K L A K N I Q B117 B118 B119 B120 B121 B122 B123 B124 Y F G A G T R L B125 B126 B127 S V L
VA	I	FASTA file	A2 A3 A4 A5 A6 A7 A8 A9 A E V E Q D P G A10 A11 A12 A13 A14 A15 A16 A17 P L S V P E G A A18 A19 A20 A21 A22 A23 A24 A25 I V S L N C T Y A26 A27 A28 A29 A36 A37 A38 A39 S N S A F Q Y F A40 A41 A42 A43 A44 A45 A46 A47 M W Y R Q Y S R A48 A49 A50 A51 A52 A53 A54 A55 K G P E L L M Y A56 A57 A58 A63 A64 A65 A66 A67 T Y S S G N K E A68 A74 A75 A76 A77 A78 A79 A80 D G R F T A Q V A81 A82 A83 A84 A85 A86 A87 A88 D K S S K Y I S A89 A90 A91 A92 A93 A94 A95 A96 L F I R D S Q P A97 A98 A99 A100 A101 A102 A103 A104 S D S A T Y L C A105 A106 A107 A108 A109 A110 A113 A114 A M R G D S S Y A115 A116 A117 A118 A119 A120 A121 A122 K L I F G S G T A123 A124 A125 A126 A127 A128 R L L V R P

CDR Sequences:

Loop	Sequence	Predicted canonical form	CDR Length
CDRB3	ASSLWEKLAKNIQY	None	14
CDRB2	FNNNVP	None	6
CDRB1	SGHDY	None	5
CDRA3	AMRGDSSYKLI	None	11
CDRA2	TYSSGN	A2-6-B	6
CDRA1	NSAFQY	None	6

Orientation and docking angles:

Angle	Value
BC2	111.51°
BC1	79.52°
BA	-60.13°
AC2	81.85°
AC1	122.01°
dc	15.86Å
Docking angle	45.26°

TCRs with similar orientations:

TCR PDB	BC2	BC1	BA	AC2	AC1	dc	TRangle Distance
5c0b_ED	111.82°	79.76°	-60.18°	82.23°	122.29°	15.88Å	0.6
5c0c_JI	111.80°	79.68°	-60.41°	81.66°	122.42°	15.89Å	0.6
5c07_JI	111.32°	79.91°	-60.76°	81.71°	122.19°	15.85Å	0.8
5c0c_ED	112.16°	79.79°	-60.27°	81.04°	122.31°	15.89Å	1.1
5c0a_ED	110.76°	79.27°	-60.64°	81.16°	122.52°	15.82Å	1.3

Antibodies with similar orientations:

Antibody PDB	HC2	HC1	HL	LC2	LC1	dc	ABangle Distance
4jkp_HL	113.93°	77.37°	-58.92°	82.11°	124.47°	15.16Å	4.3
1dlf_HL	110.03°	78.05°	-59.13°	79.41°	118.65°	15.73Å	4.8
3u7y_HL	113.61°	76.93°	-60.36°	81.15°	125.35°	15.13Å	4.8
3cvh_QR	113.65°	77.38°	-59.58°	79.78°	118.82°	15.93Å	4.9
1cl7_HL	111.63°	74.67°	-60.00°	82.67°	121.69°	16.39Å	5.0